ZygoFix

ZygoFix has developed zLOCK, a miniature spinal stabilization system without screws.

The ZygoFix Novel Implant

ZygoFix has developed the zLOCK, a miniature implant that achieves spinal fusion without using screws. zLOCK utilizes the natural construction of the vertebrae to provide spinal stability, thereby eliminating the need to insert pedicle screws. Its novel implant is inserted in the segment’s facet joints located at the back of the spine and cancels inter-vertebrae motion.

The 3D printed implant is an innovative combination of rigid and flexible elements, providing the ability to withstand the load applied on the facet joint and to fit into all shapes and sizes of joint anatomy.

Due to its unique design and placement, zLOCKprovides numerous advantages:

  • Lack of screws reduces procedure complexity and risk
  • Percutaneous, minimally invasive surgical (MIS) approach can be performed in an outpatient setting
  • Only 2 incisions (one incision on each side of the spine) for a less traumatic procedure
  • Efficient bone growth and fusion (implant has porous texture)
  • Flexible design self-adapts to almost any anatomy

The ZygoFix Opportunity

The market seeks an improved minimally invasive solution for spinal fusion that offers minimum trauma and maximum efficacy.

Learn more about how ZyogFix meets the marked need in this Q&A with CEO Ofer Levy.

The Team

  • Ofer Levy, CEO: 10+ years’ experience in medical device industry, R&D, and product development; MBA Tel Aviv University; BSc, mechanical engineering, Ben-Gurion University of the Negev
  • Uri Arnin, Co-founder and CTO: Serial medical entrepreneur; 30 years’ experience in medical device industry; 26 issued patents and 39+ pending (all in spine); former CTO Impliant (world’s first facet replacement device), CTO Spine 21 (world’s first remote-controlled spinal implant), founder and CTO ApiFix
  • Prof. Yizhar Floman, Co-founder & Medical Director: Chairman and Director of the Israel Spine Center, Assuta Hospital, Tel Aviv; former Chief of Spine Surgery, Hadassah Hebrew University Medical Center, Jerusalem, President of the Israel Orthopedic Association, member of numerous organizations, including Scoliosis Research Society, International Society for the Study of the Lumbar Spine, Spine Society of Europe, and the North American Spine Society

Trendlines’ directors: Nitza Kardish, Barak Singer

Status

Stage: Technology development
Founded: December 2016
Investor: The Trendlines Group
IP: Submitted 3 PCTs
Achievement: Started first in human (FIH) with successful results
Award:
One of the 10 best new spine technologies for 2017 (Orthopedics This Week)

The Background and Market

Spinal fusion is a surgical procedure prescribed for severe back and leg pain due to such conditions as degenerative discs or spondylolisthesis (slipped vertebra), which cause unwanted pressure on the spinal cord or nerves. The procedure is performed by relieving the pressure and stabilizing the spine. Spinal fusion is one of the most common surgical procedures – fifth in terms of OR time consumption (HCUP Statistical Brief #186).

During the fusion procedure, part of the intervertebral disc is removed and replaced with a stabilizing implant (a “cage”). To en ensure spinal stabilization is achieved, external hardware consisting of pedicle screws and rods are used to lock the vertebrae together.

Placement of the pedicle screw construct requires six incisions (minimally invasive process) and encompasses risk of misplacement which can lead to injury or revision surgery.

The market seeks a simpler, safer, and less invasive method.

According to Orthopedic Network News Spine Report (October 2017), there are 450,000 spinal infusion procedures in the United States. Zygofix estimates its global market at $1 billion based on an estimated 40% of the (relevant) market.

Now Funding

Now Funding Medical icon ZygoFix is now funding. See the presentation (PDF). Send more information about ZygoFix.

ZygoFix now funding presentation cover

Zygofix
The ZLock implant (circled) developed by Zygofix achieves facet joint fusion without screws. 

Contact

Ofer Levy, CEO
+972.52.266.4981
ofer@zygofix.com
www.zygofix.com

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