Zygofix is developing ZLock, a miniature implant that achieves spinal joint fusion and spinal stability without using screws.
The market seeks an improved minimally invasive solution for spinal fusion that offers minimum trauma and maximum efficacy.
Zygofix is developing the ZLock, a miniature implant that achieves spinal fusion and spinal stability without using screws. Its novel implant is inserted between the spine’s facet joints to create fusion and spinal stability. By inserting Zlock in the facet joints, the surgeon utilizes the natural construction of the vertebrae to provide spinal stability, and thereby eliminates the need to insert pedicle screws.
Due to its unique design and placement, ZLock provides numerous advantages:
ZLock can be used as a stand-alone fusion device or as a stabilization adjunct to other fusion procedures.
Stage: Technology development
Founded: December 2016
Investor: The Trendlines Group
IP: Submitted PCT
Disorders of the lower back (lumbar spine) such as degenerative disc disease, spondylolisthesis (slipped vertebra), and spinal stenosis (narrowing of the spinal canal) may result in severe back and leg pain. Depending on the severity, minimally invasive lumbar spinal fusion surgery may be recommended to limit movement and reduce pain.
This procedure involves (1) creating bone fusion by placing an implant in the disc space located between the two vertebrae and (2) providing additional spinal stability by inserting pedicle screws and a short rod to improve clinical outcomes.
Unfortunately, there are limitations to the current procedure, including making six incisions to insert four pedicle screws and two rods. Furthermore, 5% of all screws are misplaced and require surgical revision.
Worldwide: There are 700,000 spinal cage procedures performed annually. Zygofix estimates its global market at $772 million based on an estimated 46% of the (relevant) market.
The ZLock implant (circled) developed by Zygofix achieves facet joint fusion without screws.
Ofer Levy, CEO
Wireless, wearable vital sign monitoring system
Cryotherapy for superficial bladder cancer
Endoscopic ultrasound fine needle biopsy
Portable, automatic system for peritoneal dialysis
Device for treating ischemic stroke
Anastomotic closure device for laparoscopic bowel resection