Tissue approximation is a key step in surgery, for example during closure of skin incisions, intestinal anastomosis and anatomical repairs such as hernia and urinary incontinence. Traditional methods of suturing and stapling are effective, yet not ideal. For example, suturing is cost-effective but time-consuming and user-dependent; and while stapling offers a more rapid and consistent solution, it is significantly more expensive and associated with suboptimal cosmetic results, anastomotic strictures and potential for leaks in internal applications.
To overcome this challenge and tap the large potential of plasma for use in surgery, IonMed has developed a proprietary cold plasma surgical system. BioWeld1™, a cold plasma-based surgical system, comprises a generator, handheld piece, and single-use plasma head. To optimize tissue welding, IonMed’s solution also includes a solder derived from chitosan, which together with the cold plasma jet induces rapid clotting and tissue welding. The system can be used with various end-effectors.
Biowelding presents an effective option for a variety of skin closure applications, including skin grafts. The IonMed system has been tested for safety and efficacy of skin closure in several preclinical trials, which were followed by successful clinical studies that demonstrated closure of both laparoscopic and C-section incisions. The studies showed safety, effective closure, and a good cosmetic outcome.
Advanced tissue welding enabled by cold plasma
Stage: Business development
IP: Differentiated technology is covered by six pending patents that capture innovations in plasma energy deposition and enable practical implementation of surgical cold plasma (<40ºC)
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