CoreBone is developing a bioactive, coral-based bone graft material that provides the same qualities as organic material without the associated risks.
CoreBone has developed a highly bioactive, strong bone graft material. The patented technology embeds bioactive minerals (e.g., silicium) into the skeleton of corals during their growth process to accelerate healing and provide better connectivity. It offers the same bonelike qualities as organic material (human/animal derived) without the associated risks.
CoreBone’s strictly controlled growing environment in its coral farm preserves the coral’s natural, bonelike properties. The coral-based material provides an optimal set of properties for improved bone grafts.
Preclinical studies with CoreBone’s material demonstrated a high rate of bio-integration and connectivity with the host bone as compared with leading products in the market, as well as almost complete bone healing within two months.
Stage: Business development
Founded: December 2011
Investors: The Trendlines Group, private investors, founders
IP: U.S. patent granted (method for producing bioactive coral bone graft substitutes) in early 2015; EU/Israel in National phase
Today, implants are used more and more in dental, orthopedic, and spine procedures. In many cases, bone is insufficient, and bone grafts stimulate the growth of new bone to support and anchor the implant. Most bone graft materials in the market are derived from human and animal bone and carry the risk of disease and rejection. Synthetic materials, a fast-growing segment, lack strength.
Bone grafts from human and animal origin are in decline due to their associated risks. The synthetic bioactive product share is growing as the market seeks alternatives. The global market for orthopedic bone graft substitutes is expected to reach $3.4 billion and the global dental bone graft market $1 billion (reportlinker.com) by 2017.
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